Treatment of the primary in metastatic prostate cancer : Current Opinion in Urology

Treatment of the primary in metastatic prostate cancer : Current Opinion in Urology: garding the optimal treatment of the primary in patients diagnosed with metastatic prostate cancer.
Recent findings
Multimodal treatments offer the best chance for survival for these patients, but the optimal strategy lacks consensus. Using retrospective studies as an argument, recent articles sustain the clinical and oncological benefits of local therapies in hormone-naïve metastatic prostate cancer, represented by radical prostatectomy or radiotherapy. Through these procedures, local control of disease can be achieved, thus avoiding potential complications and further surgical interventions. Even if the current results are not evenly relevant, the treatment of the primary along with metastasis-directed therapy could improve survival and even cure-selected patients.
Summary
This article emphasizes important aspects regarding a feasible management of mPCa, with possible impact on subsequent guidelines. The expected results from ongoing trials may provide another perspective in treatment of these cases.
Correspondence to Andrei Andreşanu, MD, Center for Uronephrology and Renal Transplantation, Fundeni Clinical Institute, 258 Fundeni Avenue, 2nd District, 022328 Bucharest, Romania.